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AI-guided LNP design for targeted in vivo mRNA delivery
Messenger RNA (mRNA) therapeutics have moved from a promising idea to clinical reality, accelerating vaccine development and opening new paths ...
Platform combines proprietary AI sequence optimization, novel genetic parts, and lab validation in application-relevant cell models to improve expression and half-life, delivering top candidates in ...
To address these shortcomings, we introduce SymPcNSGA-Testing (Symbolic execution, Path clustering and NSGA-II Testing), a ...
In the field of multi-objective evolutionary optimization, prior studies have largely concentrated on the scalability of objective functions, with relatively less emphasis on the scalability of ...
Tourism development in emerging destinations requires balancing economic benefits with ecological sustainability. In this study, we investigate the case of multi-attraction tourism planning in Qujing ...
Modern seismic codes ensure life safety, but code-compliant buildings can still suffer significant economic losses from earthquake-induced damage, even during moderate events. Performance-Based ...
Abstract: Multi-objective multi-point shortest path planning problems are commonly encountered in real-world applications. Numerous path planning algorithms have been proposed to accommodate different ...
Abstract: This paper studies the multi-objective optimization problems (MOPs) of Markovian jump systems (MJSs) closed by general controllers. Firstly, the linear quadratic regulator (LQR) problem of ...
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