The advent of modern antibiotics contributed enormously to the dramatic extension of human lifespan since their discovery by virtue of their lethal and selective action against pathogenic microbes.

Cambridge scientists have discovered a light-powered chemical reaction that lets researchers modify complex drug molecules at the final stages of development. Unlike traditional methods that rely on ...

This Perspective analyses chemical reactivity through enthalpic coupling between bond making and bond breaking in elementary steps. Using enthalpic maps, mechanisms are compared, revealing shared ...

Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.