Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.
1don MSN
PV inhibitory neurons, not overall prefrontal cortex decline, linked to cocaine-seeking relapse
Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...
Neuronal sequences in the medial prefrontal cortex of the brain encode critical information associated with a procedural rule. These sequences can be explored and leveraged as novel biomarkers for ...
Neurodegenerative disease profoundly affects structures and pathways responsible for memory, cognition, and higher-order ...
Much criminal behavior derives from logical, if not laudable, sources. A wonderful example of this was seen in the old Bob Newhart television show. Newhart, playing a clinical psychologist, leans ...
It is well established in psychology that humans conceptualize emotions by features known as valence (the degree of pleasantness or unpleasantness) and arousal (the intensity of bodily reactions, such ...
For more than a century, maps of the brain have been based on how brain tissue looks under the microscope. These anatomical maps divide the brain into regions according to structural variations in the ...
3monon MSN
How the brain learns and applies rules: Sequential neuronal dynamics in the prefrontal cortex
Understanding how the brain learns and applies rules is the key to unraveling the neural basis of flexible behavior. A new study from the University of Toyama, Japan, reveals that our ability to ...
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