Extracting and analyzing relevant medical information from large-scale databases such as biobanks poses considerable challenges. To exploit such "big data," attempts have focused on large sampling ...

New genome sequencing algorithm boosts human genome completeness by 20%, improving variant detection and advancing personalized medicine.

For many diseases and chronic conditions, an individual's genes play a role in their likelihood of developing the disease. While some inherited diseases, such as cystic fibrosis or sickle cell anemia, ...

So far, it has not been possible to explain the causes of around half of all rare hereditary diseases. A Munich research team has developed an algorithm that predicts the effects of genetic mutations ...